SCIENTIFIC MEDICAL CENTER "DOSLID"
"DOSLID" is a leading biomedical research center for translational medicine in Ukraine, specializing in the study of the biological mechanisms of mental health in the context of war.
We conduct in-depth investigations into the consequences of psychological trauma, particularly post-traumatic stress disorder (PTSD), complex PTSD (CPTSD), major depressive disorder, and anxiety spectrum conditions.
STRESS AND AGING
A distinct focus of our research activity lies in examining the impact of chronic stress, particularly combat-related, on biological aging. We aim to understand the long-term effects of trauma and identify strategies to slow down age-related changes.
Specifically, we employ multi-omic laboratory methods to analyze epigenetic changes (DNA methylation), biomarkers of senescent cells, disruptions in neuroplasticity, and systemic inflammatory responses.
These approaches enable us to study the mechanisms of accelerated aging induced by psychological trauma and identify molecular targets for potential therapeutic interventions.
DIAGNOSTICS & ANALYTICS
We are committed to advancing evidence-based medicine and integrating cutting-edge diagnostic and analytical tools into clinical practice. Through innovations in research methodology, digital data processing, and interdisciplinary approaches, we are shaping new pathways for the diagnosis, prevention, and treatment of mental disorders — both in Ukraine and globally.
SCIENCE & MEDICINE
We explore the fundamental biological mechanisms underlying the onset and treatment of trauma-related disorders, with a special focus on war-related injuries and their consequences. Innovative solutions in mental health research and clinical practice.
INTERNATIONAL PROJECTS
We engage international researchers and institutions in joint projects, promoting the exchange of knowledge, resources, and expertise in the field of mental health.
INNOVATIONS
We develop cutting-edge methods for diagnosing, monitoring, and personalizing the treatment of mental health disorders by integrating modern digital solutions, biomarkers, artificial intelligence, and more into our work.
HUMANISM
We promote a global understanding of mental health challenges by ensuring access to a diverse patient population and seeking effective solutions to support and improve their quality of life.
We are open to partnerships and welcome new forms of collaboration aimed at advancing science and improving global mental well-being
TEAM of DOSLID
. HEAD OF THE RESEARCH DEPARTMENT
DMYTRO MARTSENKOVSKYI
Psychiatrist, child psychiatrist, PhD, a leading expert in psychiatry who combines clinical practice with cutting-edge research.
SCIENTIST
VICTOR DOSENKO
Geneticist, pathophysiologist, Doctor of Medical Sciences, Professor — a distinguished scientist with extensive experience in both clinical and academic research.
SCIENTIST
OKSANA SULAIEVA
Pathologist, Doctor of Medical Sciences, Professor — a recognized expert in the field of anatomical pathology, contributing significantly to the advancement of diagnostic methodologies.
CLINICIAN
ANTON SAVCHENKO
Psychiatrist, a specialist known for his compassionate approach to mental health and commitment to evidence-based treatment methods.
OUR PROJECTS
Ukrainian National Initiative for Trauma Study (UNITY)
UNITY is a Ukrainian interdisciplinary research initiative that combines clinical, psychometric, and biological approaches to comprehensively study the effects of military trauma on mental and physical health throughout life.
- MORE DETAILS
The initiative investigates the impact of full-scale war in Ukraine on military personnel and civilians, adults and children, combining mental health assessments with analyses of neurobiological, metabolic, and immune processes. This integrated approach provides a deeper understanding of how psychological trauma interacts with the body, development, and recovery processes.
UNITY was created as a Ukrainian scientific platform in collaboration with international partners, with a focus on building an evidence base for clinical care, rehabilitation, and long-term solutions in the field of mental health in wartime and post-war recovery.
Main areas of work:
- mental disorders associated with trauma (PTSD, depression, anxiety disorders);
- traumatic brain injury and neuropsychiatric consequences;
- biological and molecular markers of stress and trauma;
- psychometrics, diagnostics, and adaptation of assessment tools;
- the impact of war on parents, children, and intergenerational processes;
- Recovery, rehabilitation, and effective interventions.
Research within the initiative:
RESEARCH PROJECT
Validation of the International Trauma Interview (ITI)
The DOSLID scientific team translated the International Trauma Interview (ITI) — a newly developed clinical tool for diagnosing PTSD and CPTSD based on ICD-11 criteria — into Ukrainian. The translation has been approved by the instrument's original developers. Currently, the team is conducting a validation study within the Ukrainian population.
SCIENTIFIC STUDY
"Study of Epigenetic and Metabolic Mechanisms of Mental Health Disorders in Individuals Exposed to Psychological Trauma Due to Warfare: Impact on Aging and Longevity"
- DETAILS
Project duration – 1.5 years
As of early 2025:
- Involvement of 650 patients with the collection of biological material for further testing,
- Collected samples were tested for biomarkers of chronic stress.
- Additional analyses were conducted to assess levels of senescent cell biomarkers and DNA methylation.
- Based on the obtained results, four scientific manuscripts have already been prepared for submission to international peer-reviewed journals.
Partnerships
UNITY is implemented in collaboration with Ukrainian and international academic, clinical, and research institutions.
We are open to collaboration with scientists, clinicians, institutions, and public organizations that share our scientific and ethical principles.
Scientific research:
SCIENTIFIC STUDY
“Single-Center Randomized Double-Blind Controlled Clinical Trial of Ketamine-Assisted Integrative Psychotherapy in Veterans with Treatment-Resistant Post-Traumatic Stress Disorder (PTSD)”
- DETAILS
DOSLID was actively involved in the research team of this study, contributing to:
- Definition of the study’s objective,
- Formulation of the research tasks,
- Development of the methodology,
- Design of the trial protocol.
The team carried out a thorough selection of tools for data collection and analysis, ensuring compliance with contemporary scientific and clinical research standards.
Additionally, the research team successfully obtained ethical committee approval, confirming adherence to ethical principles and the protection of participants' rights throughout the study.
WE ORGANIZE SCIENTIFIC CONFERENCES
Since 2023, during June (PTSD Awareness Month), DOSLID has been organizing scientific conferences with international participation. The purpose of these events is to develop the following areas:
DIAGNOSTICS
Advancing modern methods for PTSD diagnosis, including biomarkers and other cutting-edge approaches.
SUPPORT FOR AFFECTED INDIVIDUALS
Research and development of effective support methods for people with PTSD.
AWARENESS & EDUCATION
Enhancing understanding and awareness of PTSD among the general public, medical professionals, and mental health specialists.
ACCESSIBILITY
Ensuring equal access to diagnosis and treatment for everyone in need of support.
"Traumatic stress and post-traumatic growth"
The conference was attended by 100 participants and 300 online listeners.
Among the speakers:
- Ukrainian specialists
- International scientists
- Dmytro Martsenkovskyi (Department of Psychiatry and Narcology, Bogomolets National Medical University; Medical Center “DOSLID”, Kyiv, Ukraine)
- Kseniia Voznitsyna, Tetiana Sirenko (State Institution “Lisova Polyana Mental Health Center of the Ministry of Health of Ukraine”, Kyiv, Ukraine)
- Viktor Dosenko, Hanna Shcherbakova (Department of General and Molecular Pathophysiology, Bogomolets Institute of Physiology, CSD LAB Medical Laboratory, Kyiv, Ukraine)
- Dmytro Assonov (Department of Medical Psychology, Psychosomatic Medicine and Psychotherapy, Bogomolets National Medical University, Kyiv, Ukraine);
- Yelyzaveta Korniyko (Master's student of the "Health care" Erasmus, Ecole des Hautes Etudes de Santé Publique, France)
- Neil Greenberg (Royal College of Psychiatrists, London, UK).
- Rachel Christina Bacham (Department of Psychopathology and Clinical Intervention, Department of Psychology, University of Zurich, Zurich, Switzerland);
- Adam D. Brown (Department of Psychology, New School for Social Research, New York, USA);
- Charles R. Marmar (Center for Precision Medicine in Alcohol Use Disorders and PTSD, Department of Psychiatry, New York University Grossman School of Medicine; Department of Psychiatry, New York University Grossman School of Medicine; Stephen and Alexandra Cohen Veterans Center for PTSD and TBI, Department of Psychiatry, New York University Grossman School of Medicine, New York, NY, USA)
- Alex Gershanov (International trauma expert, director of psycho-educational programs at Israel Trauma Coalition, Tel Aviv, Israel)
"Stress-Associated Disorders: Implementing Global Best Practices in Diagnosis and Treatment"
The conference gathered 150 in-person participants and approximately 500 online attendees.
- Ukrainian specialists
- International scientists
- Dmytro Martsenkovskyi (Department of Psychiatry and Narcology Bogomolets National Medical University, DOSLID Medical Center, Kyiv)
- Viktor Dosenko (Department of General and Molecular Pathophysiology, Bogomolets Institute of Physiology, CSD Medical Laboratory)
- Viktor Komarenko (3rd Separate Assault Brigade, Captain, Armed Forces of Ukraine), Kseniia Voznitsyna (Director, “Lisova Polyana” Mental Health Center, Ministry of Health of Ukraine)
- Anton Savchenko (DOSLID Medical Center)
- Tatiana Tsilenko (Psychologist in the field of trauma therapy and grief therapy)
- Serhii Danylov (Tech startup "Anima")
- Philip Hyland (Department of Psychology, Maynooth University, Ireland)
- Thanos Karatzias (School of Health and Social Care, Edinburgh Napier University, Scotland)
- Mark Shevlin (School of Psychology, Ulster University, Northern Ireland)
COLLABORATION & CONTACTS
DOSLID seeks to collaborate with researchers and institutions worldwide to foster innovation and improve the lives of individuals affected by PTSD, major depressive disorder (MDD), and anxiety disorders.
In this regard, we are actively interested in conducting research within the framework of national and international grant programs.